Gustav Mahler and Emanuel Libman: bacterial endocarditis in 1911.
نویسنده
چکیده
was diagnosed definitively by Emanuel Libman (1872-1946) and his assistant, George Baehr (1887-1978), who at the time, together with William Osler and Thomas Horder in England, were the world's greatest authorities on endocarditis. In 1983 I initiated a search for the detailed bacteriological records known to have been kept by Dr Baehr. Dr ArnoldM Weissler, of Denver, Colorado, traced them to the National Library of Medicine, Bethesda, through Dr George L Engel, nephew of Dr Libman, and Dr Manfred Waserman, formerly of the National Library of Medicine. The records, from the Mount Sinai Hospital, New York, had been deposited there after Dr Libman's death. I present them here in relation to some of the biographical and clinical details of Mahler's illness and to the state of knowledge of bacterial endocarditis in 1911, a time when many of the outstanding problems of the disease were being solved.
منابع مشابه
Libman-Sacks Endocarditis
In 1924 Libman and Sacks published an account of atypical, sterile, verrucous vegetations on the heart in systemic lupus erythematosus (SLE). [1] Clusters of verrucae, looking like mulberries, were described on the ventricular surface of the posterior leaflet of the mitral valve and found at postmortem. The leaflet and the chordae tendinae are often adherent to the endocardium of the ventricula...
متن کامل[Severe mitral regurgitation in Libman-Sacks endocarditis. Conservative surgery].
Libman-Sacks endocarditis is a classic but rarely symptomatic manifestation of systemic lupus erythematosus, and valvular surgery is needed in a few cases. We present a patient with systemic lupus erythematosus and Libman-Sacks endocarditis that progressed rapidly to severe mitral regurgitation that needed surgery; surgical valve repair was decided upon. The literature on this topic is reviewed.
متن کاملMitral valve surgery for mitral regurgitation caused by Libman-Sacks endocarditis: a report of four cases and a systematic review of the literature
Libman-Sacks endocarditis of the mitral valve was first described by Libman and Sacks in 1924. Currently, the sterile verrucous vegetative lesions seen in Libman-Sacks endocarditis are regarded as a cardiac manifestation of both systemic lupus erythematosus (SLE) and the antiphospholipid syndrome (APS). Although typically mild and asymptomatic, complications of Libman-Sacks endocarditis may inc...
متن کاملLibman-Sacks endocarditis in patients with systemic lupus erythematosus with secondary antiphospholipid syndrome
Background: Libman-Sacks endocarditis (LSE) is characterized by sterile lesions that commonly affect the aortic and mitral heart valves. Antiphospholipid syndrome (APS) and systemic lupus erythematosus (SLE) have been associated with LSE. Cardiac manifestations including LSE could be interrelated with other manifestations and early diagnosis could help in preventing further complications. Case...
متن کاملPerforated mitral valve aneurysm associated with Libman-Sacks endocarditis.
The perforation of a mitral valve aneurysm is a rare disease which induces acute mitral regurgitation and is usually induced by infective endocarditis; however, in this case report, acute heart failure was caused by a perforated mitral valve aneurysm that was speculated to be due to Libman-Sacks endocarditis with systemic lupus erythematosis and secondary anti-phospholipid syndrome. Mitral valv...
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ورودعنوان ژورنال:
- British medical journal
دوره 293 6562 شماره
صفحات -
تاریخ انتشار 1986